Article

ADSCs increase the autophagy of chondrocytes through decreasing miR-7-5p in Osteoarthritis rats by targeting ATG4A

2022-09-23

Abstract excerpt

<h4>Background: </h4> Osteoarthritis (OA) is a highly degenerative joint disease, mainly companying with progressive destruction of articular cartilage. Adipose-derived stromal cells (ADSCs) therapy enhances articular cartilage repair, extracellular matrix (ECM) synthesis and attenuates joints inflammation, but specific mechanisms of therapeutic benefit remain poorly understood. This study aimed to clarify the the...

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Literature Corpus work: 7650ad5d-05dd-521e-8d2d-1a3f0a985bc3
DOI: 10.21203/rs.3.rs-1848320/v1

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