Article

Autophagy-related genes and pathways was associated with osteoarthritis pathogenesis

2023-01-12

Abstract excerpt

<h4>Background: </h4> Patients with osteoarthritis have musculoskeletal-related chronic disability, leading to the high pain intensity. Explaining the molecular mechanisms of osteoarthritis is critial for the diagnosis and cure. Therefore, This research aimed to find key candidate genes involved in osteoarthritis pathogenesis. <h4>Methods: </h4> We identified differentially expressed genes by integrating multiple...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6f646d5c-1c0e-5139-92a7-e934c6574383
DOI: 10.21203/rs.3.rs-2440945/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Autophagy-related genes and pathways was associated with osteoarthritis pathogenesisDOI 10.21203/rs.3.rs-2440945/v1Read

Comprehensive Analysis of Key Genes, Signaling Pathways and miRNAs in Human Knee Osteoarthritis: Based on BioinformaticsSemantic proximity Read

Comprehensive analysis of GEO data reveals potential miRNA-mRNA regulation axis and analyses the role of key regulatory axis on osteoarthritisSemantic proximity Read

Identification and experimental verification of key genes related to the Ras signaling pathway and the Hippo signaling pathway in osteoarthritis based on transcriptome dataSemantic proximity Read

Identification of the osteoarthritis signature gene PDK1 by machine learning and its regulatory mechanisms on chondrocyte autophagy and apoptosisSemantic proximity Read

Identification of autophagy-related genes in osteoarthritis articular cartilage and their roles in immune infiltrationSemantic proximity Read

A gene expression analysis and immune infiltration between lesioned and preserved subchondral bone in osteoarthritisSemantic proximity Read

Autophagy related gene CEP55 is a potential biomarker for osteoarthritisSemantic proximity Read

Identification and Validation of Autophagy-Related Genes in Osteoarthritis through Bioinformatics and Machine LearningSemantic proximity Read

Identification and validation of novel characteristic genes based on multi-tissue osteoarthritisSemantic proximity Read

Identification of osteoarthritis-characteristic genes and immunological micro-environment features by bioinformatics and machine learningSemantic proximity Read

Classification of distinct osteoarthritis subtypes with different knee joint tissues by gene expression profilesSemantic proximity Read

Identification of specific biomarkers and pathways in the synovial tissues of patients with osteoarthritis in comparison to rheumatoid arthritisSemantic proximity Read