Article
Autophagy and apoptosis: regulatory factors of chondrocyte phenotype transition in osteoarthritis.
Human cell - 1 Jul 2023
Liu Zhibo, Wang Ting, Sun Xianding, Nie Mao
Abstract excerpt
Osteoarthritis (OA) is the main pathogenic factor in diseases that cause joint deformities. As the main manifestation of the progress of OA, cartilage degradation has been closely associated with the degeneration of chondrocytes, which is induced by inflammatory factors and other trauma factors. Autophagy and apoptosis are the main mechanisms for cells to maintain homeostasis and play crucial roles in OA. Under...
Topics
- Humans
- Chondrocytes
- Osteoarthritis
- Apoptosis
- Phenotype
- Autophagy