Article

Adipose-Derived Stem Cell Sheets Enhance Diced Cartilage Graft Survival via Regulation of the Autophagy–Pyroptosis Axis

2026-07-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Autologous diced costal cartilage is widely used in rhinoplasty and auricular reconstruction; however, long-term graft survival is often compromised by oxidative stress, inflammation, and insufficient vascularization after transplantation. Emerging evidence suggests that NLRP3/Caspase-1/GSDMD-mediated pyroptosis and impaired autophagy contribute to chondrocyte...

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Literature Corpus work: 0b34300a-646b-5429-b2cc-cf9e714c68dd
DOI: 10.21203/rs.3.rs-9687934/v1

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