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Article

MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis

1 Jan 2017

Abstract excerpt

Osteoarthritis (OA) is a debilitating degenerative disease of the articular cartilage with a multifactorial etiology. Aging, the main risk factor for OA development, is associated with a systemic oxidative and inflammatory phenotype. Autophagy is a central housekeeping system that plays an antiaging role by supporting the clearance of senescence-associated alterations of macromolecules and organelles. Autophagy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28713485
DOI: 10.1155/2017/3720128

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