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Exosomes derived from mesenchymal stem cells inhibit catabolism in human chondrocytes by activating autophagy via inhibition of the NF-κB pathway

2020-10-01

Abstract excerpt

<title>Abstract</title> <p><bold>Objective: </bold>We aimed to determine the significance of MSC-derived exosomes (MSC-Exos) in chondrocyte autophagy under normal and inflammatory conditions.<bold>Design: </bold>Human umbilical cord-derived MSCs (hMSCs) were cultured in vitro. hMSC-Exos( EX） were isolated by an ultracentrifugation method. Transmission electron microscopy and western analysis were used to identify...

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Literature Corpus work
c4987d66-e4f0-57d9-862f-14fea943d43c
DOI
10.21203/rs.3.rs-83574/v1
Open publication

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Exosomes derived from mesenchymal stem cells inhibit catabolism in human chondrocytes by activating autophagy via inhibition of the NF-κB pathwayDOI 10.21203/rs.3.rs-83574/v1
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