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Article

Modulated Autophagy by MicroRNAs in Osteoarthritis Chondrocytes

8 May 2019

Abstract excerpt

Osteoarthritis (OA) is a chronic joint disease characterized by articular cartilage regression. The etiology of OA is diverse, the exact pathogenesis of which remains unclear. Autophagy is a conserved maintenance mechanism in eukaryotic cells. Dysfunction of chondrocyte autophagy is regarded as a crucial pathogenesis of cartilage degradation in OA. MircoRNAs (miRNAs) are a category of small noncoding RNAs, acting...

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PMID: 31205933
DOI: 10.1155/2019/1484152

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