Article

Sex-dependent adipose glucose partitioning by the mitochondrial pyruvate carrier

2024-05-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> The mitochondrial pyruvate carrier (MPC) occupies a critical node in intermediary metabolism, prompting interest in its utility as a therapeutic target for the treatment of obesity and cardiometabolic disease. Dysregulated nutrient metabolism in adipose tissue is a prominent feature of obesity pathophysiology, yet the functional role of adipose MPC has not been explored. We i...

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Literature Corpus work: 7469599c-795b-51a3-a3bc-3800f80eef22
DOI: 10.1101/2024.05.11.593540

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