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Article

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes.

Cell metabolism - 1 Feb 2005

Maeda Kazuhisa, Cao Haiming, Kono Keita, Gorgun Cem Z, Furuhashi Masato, Uysal Kadir T, Cao Qiong, Atsumi Genichi, Malone Harry, Krishnan Bala, Minokoshi Yasuhiko, Kahn Barbara B, Parker Rex A, Hotamisligil Gökhan S

Abstract excerpt

Fatty acid binding proteins (FABPs) are cytosolic fatty acid chaperones whose biological role and mechanisms of action are not well understood. Here, we developed mice with targeted mutations in two related adipocyte FABPs, aP2 and mal1, to resolve their role in systemic lipid, glucose, and energy metabolism. Mice lacking aP2 and mal1 exhibited a striking phenotype with strong protection from diet-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16054052
DOI: 10.1016/j.cmet.2004.12.008

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SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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