Article

A novel test for detecting gene-gene interactions in trio studies

2015-06-25

Abstract excerpt

Epistasis plays a significant role in the genetic architecture of many complex phenotypes in model organisms. To date, there have been very few interactions replicated in human studies due in part to the multiple hypothesis burden implicit in genome-wide tests of epistasis. Therefore, it is of paramount importance to develop the most powerful tests possible for detecting interactions. In this work we develop a new...

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Literature Corpus work: 7420df6e-8cd2-5971-935b-6d17b50c4bed
DOI: 10.1101/021469

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