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Article

TrioMDR: Detecting SNP interactions in trio families with model-based multifactor dimensionality reduction.

Genomics - 1 Sept 2019

Liu Jie, Yu Guoxian, Ren Yazhou, Guo Maozu, Wang Jun

Abstract excerpt

Single nucleotide polymorphism (SNP) interactions can explain the missing heritability of common complex diseases. Many interaction detection methods have been proposed in genome-wide association studies, and they can be divided into two types: population-based and family-based. Compared with population-based methods, family-based methods are robust vs. population stratification. Several family-based methods have...

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PMID: 30055230
DOI: 10.1016/j.ygeno.2018.07.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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