Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detecting disease variants in case-parent trio studies using the bioconductor software package trio.

Genetic epidemiology - 1 Sept 2014

Schwender Holger, Li Qing, Neumann Christoph, Taub Margaret A, Younkin Samuel G, Berger Philipp, Scharpf Robert B, Beaty Terri H, Ruczinski Ingo

Abstract excerpt

Case-parent trio studies are commonly employed in genetics to detect variants underlying common complex disease risk. Both commercial and freely available software suites for genetic data analysis usually contain methods for case-parent trio designs. A user might, however, experience limitations with these packages, which can include missing functionality to extend the software if a desired analysis has not been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genetic Variation

Share to Genotype

Share to Parents

Share to Polymorphism, Single Nucleotide

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 25048299
DOI: 10.1002/gepi.21836
PMCID: PMC4139708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detecting disease variants in case-parent trio studies using the bioconductor software package trio.PMID 25048299Read ↗

Efficient genome-wide association testing of gene-environment interaction in case-parent trios.Semantic proximity Read ↗

Review of statistical methodologies for the detection of parent-of-origin effects in family trio genome-wide association data with binary disease traits.Semantic proximity Read ↗

A Novel Test for Detecting SNP-SNP Interactions in Case-Only Trio Studies.Semantic proximity Read ↗

TrioMDR: Detecting SNP interactions in trio families with model-based multifactor dimensionality reduction.Semantic proximity Read ↗

A novel test for detecting gene-gene interactions in trio studiesSemantic proximity Read ↗

Combining case-control and case-trio data from the same population in genetic association analyses: overview of approaches and illustration with a candidate gene study.Semantic proximity Read ↗

Distinguishing the effects of maternal and offspring genes through studies of "case-parent triads".Semantic proximity Read ↗

Benchmarking statistical methods for analyzing parent-child dyads in genetic association studies.Semantic proximity Read ↗

Disease genomics: Triaging risk variants in the non-coding genome.Semantic proximity Read ↗

TRIO RVEMVS: A Bayesian framework for rare variant association analysis with expectation-maximization variable selection using family trio data.Semantic proximity Read ↗

An efficient study design to test parent-of-origin effects in family trios.Semantic proximity Read ↗

Disentangling pooled triad genotypes for association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.