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Article

Combining disease models to test for gene-environment interaction in nuclear families.

Biometrics - 1 Dec 2011

Hoffmann Thomas J, Vansteelandt Stijn, Lange Christoph, Silverman Edwin K, DeMeo Dawn L, Laird Nan M

Abstract excerpt

It is useful to have robust gene-environment interaction tests that can utilize a variety of family structures in an efficient way. This article focuses on tests for gene-environment interaction in the presence of main genetic and environmental effects. The objective is to develop powerful tests that can combine trio data with parental genotypes and discordant sibships when parents' genotypes are missing. We...

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Source

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Identifiers

PMID: 21401569
DOI: 10.1111/j.1541-0420.2011.01581.x
PMCID: PMC3120904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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