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Article

A data-smoothing approach to explore and test gene-environment interaction in case-parent trios.

Statistical applications in genetics and molecular biology - 1 Apr 2014

Shin Ji-Hyung, Infante-Rivard Claire, McNeney Brad, Graham Jinko

Abstract excerpt

Complex traits result from an interplay between genes and environment. A better understanding of their joint effects can help refine understanding of the epidemiology of the trait. Various tests have been proposed to assess the statistical interaction between genes and the environment (G×E) in case-parent trio data. However, these tests can lose power when the form of G×E departs from that for which the test was...

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PMID: 24413219
DOI: 10.1515/sagmb-2013-0023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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