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Article

An efficient gene-gene interaction test for genome-wide association studies in trio families.

Bioinformatics (Oxford, England) - 15 Jun 2016

Sung Pei-Yuan, Wang Yi-Ting, Yu Ya-Wen, Chung Ren-Hua

Abstract excerpt

MOTIVATION: Several efficient gene-gene interaction tests have been developed for unrelated case-control samples in genome-wide association studies (GWAS), making it possible to test tens of billions of interaction pairs of single-nucleotide polymorphisms (SNPs) in a reasonable timeframe. However, current family-based gene-gene interaction tests are computationally expensive and are not applicable to genome-wide...

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Identifiers

PMID: 26873927
DOI: 10.1093/bioinformatics/btw077
PMCID: PMC5939888

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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