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Article

Simple modeling of Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technology

2023-09-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold><italic> </italic>Cerebral organoids (COs) are the most advanced <italic>in vitro</italic>models that resemble the human brain. Use of COs as a model for human Alzheimer’s disease (AD), among other brain diseases, has recently gained attention. This study aimed to develop a human AD CO model, using normal human pluripotent stem cells (hPSCs), that recapitulates th...

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Literature Corpus work
73558cc6-c795-5496-9abf-9040a23d9d27
DOI
10.21203/rs.3.rs-2817666/v1
Open publication

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