Article

Generation of an Alzheimer’s Disease Model Derived from Induced Pluripotent Stem Cells with an APP Gene Mutation

2024-05-06

Abstract excerpt

Alzheimer’s disease (AD), the most common cause of dementia, is characterized by disruptions in memory, cognition, and personality, significantly impacting morbidity and mortality rates among older adults. However, the exact pathophysiological mechanism of AD remains unknown, and effective treatment options for AD are still lacking. Human induced pluripotent stem cells (iPSC) are emerging as promising platforms fo...

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Literature Corpus work: b5f6829b-15a8-54f7-8f80-c6f74abe3ed3
DOI: 10.20944/preprints202405.0243.v1

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