Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Induced Pluripotent Stem Cells and the Modelling of Alzheimer’s Disease: The Human Brain Outside the Dish

30 Sept 2017

Abstract excerpt

BACKGROUND: Neurodegenerative diseases like Alzheimer's Disease (AD) are a global health issue primarily in the elderly. Although AD has been investigated using primary cultures, animal models and post-mortem human brain tissues, there are currently no effective treatments. SUMMARY: With the advent of induced pluripotent stem cells (iPSCs) reprogrammed from fully differentiated adult cells such as skin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Ethics and Regulation
Share to Neurogenesis and neuroplasticity mechanisms
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29151989
DOI: 10.2174/1874205x01711010027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Induced Pluripotent Stem Cells and the Modelling of Alzheimer’s Disease: The Human Brain Outside the DishPMID 29151989Read ↗

Alzheimer's Disease Modeling: Ups, Downs, and Perspectives for Human Induced Pluripotent Stem CellsSemantic proximity Read ↗

Reprogramming the Brain—iPSC Models Illuminating the Pathogenesis and Treatment of Alzheimer’s Disease and Other DementiasSemantic proximity Read ↗

Generation of an Alzheimer’s Disease Model Derived from Induced Pluripotent Stem Cells with an APP Gene MutationSemantic proximity Read ↗

Human-induced pluripotent stem cells: potential for neurodegenerative diseases.Semantic proximity Read ↗

Stem Cell Therapies in Alzheimer’s Disease: Applications for Disease ModelingSemantic proximity Read ↗

Human stem cell models of dementiaSemantic proximity Read ↗

Dissecting the complexities of Alzheimer disease with in vitro models of the human brain.Semantic proximity Read ↗

Neurodegeneration in a dish: advancing human stem-cell-based models of Alzheimer's disease.Semantic proximity Read ↗

Alzheimer's disease in a dish: promises and challenges of human stem cell models.Semantic proximity Read ↗

Simple modeling of Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technologySemantic proximity Read ↗

Simple modeling of familial Alzheimer’s disease using human pluripotent stem cell-derived cerebral organoid technologySemantic proximity Read ↗

Alzheimer's disease and synapse Loss: What can we learn from induced pluripotent stem Cells?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.