Article
Invited review: Identifying new mouse models of cardiovascular disease: a review of high-throughput screens of mutagenized and inbred strains.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Apr 2003
Svenson Karen L, Bogue Molly A, Peters Luanne L
Abstract excerpt
The mouse is a proven model for studying human disease. Many strains exist that exhibit either natural or engineered genetic variation and thereby enable the elucidation of pathways involved in the development of cardiovascular disease. Although those mouse models have been fundamental to advancing our knowledge base, we are still at an early stage in understanding how genes contribute to complex disorders. There...
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