Article
Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy.
American journal of physiology. Heart and circulatory physiology - 1 May 2007
Barrick Cordelia J, Rojas Mauricio, Schoonhoven Robert, Smyth Susan S, Threadgill David W
Abstract excerpt
Left ventricular hypertrophy (LVH), a risk factor for cardiovascular morbidity and mortality, is commonly caused by essential hypertension. Three geometric patterns of LVH can be induced by hypertension: concentric remodeling, concentric hypertrophy, and eccentric hypertrophy. Clinical studies suggest that different underlying etiologies, genetic modifiers, and risk of mortality are associated with LVH geometric...
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