Article

Systems genetic dissection of Alzheimer’s disease brain gene expression networks

2024-10-04

Abstract excerpt

<h4>ABSTRACT</h4> In Alzheimer’s disease (AD), changes in the brain transcriptome are hypothesized to mediate the impact of neuropathology on cognition. Gene expression profiling from postmortem brain tissue is a promising approach to identify causal pathways; however, there are challenges to definitively resolve the upstream pathologic triggers along with the downstream consequences for AD clinical manifestation...

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Literature Corpus work: 715b9e54-a4d5-5f6d-bae2-a19738588ca6
DOI: 10.1101/2024.10.04.616661

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