Article

Genetic Dependency of Alzheimer’s Disease-associated Genes Across Cells and Tissue Types

2021-01-04

Abstract excerpt

<title>Abstract</title> <p>Background Multiple genes with genetic variants or expression changes associated with Alzheimer’s disease (AD) have been identified. Altering their expression and activity levels serve as potential therapeutic strategies, yet the cellular implications of such alterations remain largely unknown. Methods Cellular dependencies of 105 AD-associated genes, previously identified by genome-wid...

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Literature Corpus work: 6cf9363a-788b-521f-887f-3f12d741a421
DOI: 10.21203/rs.3.rs-136393/v1

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