Article

Functional dissection of Alzheimer’s disease brain gene expression signatures in humans and mouse models

2019-01-03

Abstract excerpt

<h4>SUMMARY</h4> Human brain transcriptomes can highlight biological pathways associated with Alzheimer’s disease (AD); however, challenges remain to link expression changes with causal triggers. We have examined 30 AD-associated, gene coexpression modules from human brains for overlap with 251 differentially-expressed gene sets from mouse brain RNA-sequencing experiments, including from models of AD and other ne...

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Literature Corpus work: 247e6a75-d1ba-582d-a536-cf697fbb4739
DOI: 10.1101/506873

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