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Senescent cell networks link matrix remodeling and vascular dysfunction in human fibroids

2026-08-07

Abstract excerpt

Uterine fibroids (leiomyomas) are highly prevalent benign tumors defined by excessive extracellular matrix (ECM) deposition, altered vascular structure, and progressive tissue stiffening, yet the cellular programs that coordinate these features remain poorly understood. Cellular senescence has been implicated in fibroid biology, but whether senescence represents a uniform state or distinct, functionally specialize...

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Identifiers and source

Literature Corpus work
4e26a748-dfb9-5fda-938a-b094acadcab4
DOI
10.64898/2026.08.06.743362
Open publication

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Senescent cell networks link matrix remodeling and vascular dysfunction in human fibroidsDOI 10.64898/2026.08.06.743362
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