Article

Generating human neural diversity with a multiplexed morphogen screen in organoids

2023-06-01

Abstract excerpt

Morphogens choreograph the generation of remarkable cellular diversity in the developing nervous system. Differentiation of stem cells toward particular neural cell fates in vitro often relies upon combinatorial modulation of these signaling pathways. However, the lack of a systematic approach to understand morphogen-directed differentiation has precluded the generation of many neural cell populations, and knowle...

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Literature Corpus work: 46da1584-8839-50cc-97b0-c215d6c07e58
DOI: 10.1101/2023.05.31.541819

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