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Genome-wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measures

2025-02-13

Abstract excerpt

<h4>Background</h4> Genome-wide association studies (GWAS) have identified over 1,000 blood pressure (BP) loci and over 80 loci for Alzheimer’s disease (AD). Considering BP is an AD risk factor, identifying pleiotropy in BP and cognitive performance measures may indicate mechanistic links between BP and AD. <h4>Methods</h4> Genome-wide scans for pleiotropy in BP variables—systolic (SBP), diastolic (DBP), mean arte...

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Literature Corpus work
6fe4232a-1833-589c-8743-896b5ef0483c
DOI
10.1101/2025.02.11.25322014
Open publication

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Genome-wide pleiotropy analysis of longitudinal blood pressure and harmonized cognitive performance measuresDOI 10.1101/2025.02.11.25322014
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