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Article

Lipid associated polygenic enrichment in Alzheimer’s disease

2018-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Cardiovascular (CV) and lifestyle associated risk factors (RFs) are increasingly recognized as important for Alzheimer’s disease (AD) pathogenesis. Beyond the ∊4 allele of apolipoprotein E ( APOE ), comparatively little is known about whether CV associated genes also increase risk for AD (genetic pleiotropy). Using large genome-wide association studies (GWASs) (total n > 500,000 cases and cont...

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Literature Corpus work
cc4170ab-59c3-5bc8-84e2-8e585692ba7b
DOI
10.1101/383844
Open publication

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