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Article

Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis.

GeroScience - 1 Feb 2022

Kulminski Alexander M, Loiko Elena, Loika Yury, Culminskaya Irina

Abstract excerpt

Epidemiological studies report beneficial associations of higher educational attainment (EDU) with Alzheimer's disease (AD). Prior genome-wide association studies (GWAS) also reported variants associated with AD and EDU separately. The analysis of pleiotropic associations with these phenotypes may shed light on EDU-related protection against AD. We performed pleiotropic meta-analyses using Fisher's method and...

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Identifiers

PMID: 34743297
DOI: 10.1007/s11357-021-00484-1
PMCID: PMC8572080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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