Article

Hi-TOM: a platform for high-throughput tracking of mutations induced by CRISPR/Cas systems

2017-12-18

Abstract excerpt

The CRISPR/Cas system has been extensively applied to make precise genetic modifications in various organisms. Despite its importance and widespread use, large-scale mutation screening remains time-consuming, labour-intensive and costly. Here, we describe a cheap, practicable and high-throughput screening strategy that allows parallel screening of 96 × N (N denotes the number of targets) genome-modified sites. The...

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Literature Corpus work: 6fcf4afb-89b7-5f93-a7fe-0a6f217edad1
DOI: 10.1101/235903

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