Article
CRISPR-detector: fast and accurate detection, visualization, and annotation of genome-wide mutations induced by genome editing events.
Journal of genetics and genomics = Yi chuan xue bao - 1 Aug 2023
Huang Lei, Wang Dan, Chen Haodong, Hu Jinnan, Dai Xuechen, Liu Chuan, Li Anduo, Shen Xuechun, Qi Chen, Sun Haixi, Zhang Dengwei, Chen Tong, Jiang Yuan
Abstract excerpt
The leading-edge CRISPR/CRISPR-associated technology is revolutionizing biotechnologies through genome editing. To track on/off-target events with emerging new editing techniques, improved bioinformatic tools are indispensable. Existing tools suffer from limitations in speed and scalability, especially with whole-genome sequencing (WGS) data analysis. To address these limitations, we have developed a...
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