Article

A systematic search for RNA structural switches across the human transcriptome

2023-03-12

Abstract excerpt

<h4>ABSTRACT</h4> RNA structural switches are key regulators of gene expression in bacteria, yet their characterization in Metazoa remains limited. Here we present SwitchSeeker, a comprehensive computational and experimental approach for systematic identification of functional RNA structural switches. We applied SwitchSeeker to the human transcriptome and identified 245 putative RNA switches. To validate our appr...

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Literature Corpus work: 6f08166d-e380-5e70-902f-fc3d0d5ba29c
DOI: 10.1101/2023.03.11.532161

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