Article

An <i>in silico</i> map of the SARS-CoV-2 RNA Structurome

2020-04-18

Abstract excerpt

SARS-CoV-2 is a positive-sense single-stranded RNA virus that has exploded throughout the global human population. This pandemic coronavirus strain has taken scientists and public health researchers by surprise and knowledge of its basic biology (e.g. structure/function relationships in its genomic, messenger and template RNAs) and modes for therapeutic intervention lag behind that of other human pathogens. In thi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6a5b0514-395f-5de3-9e01-6922e638dc48
DOI: 10.1101/2020.04.17.045161

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An <i>in silico</i> map of the SARS-CoV-2 RNA StructuromeDOI 10.1101/2020.04.17.045161Read

A map of the SARS-CoV-2 RNA structuromeSemantic proximity Read

Comprehensive in-vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanismsSemantic proximity Read

The global and local distribution of RNA structure throughout the SARS-CoV-2 genomeSemantic proximity Read

Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elementsSemantic proximity Read

Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cellsSemantic proximity Read

The architecture of the SARS-CoV-2 RNA genome inside virionSemantic proximity Read

The architecture of SARS-CoV-2 transcriptomeSemantic proximity Read

The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2Semantic proximity Read

SARS-CoV-2 ribosomal frameshifting pseudoknot: Improved secondary structure prediction and detection of inter-viral structural similaritySemantic proximity Read

Lessons Learned and Yet-to-Be Learned on the Importance of RNA Structure in SARS-CoV-2 ReplicationSemantic proximity Read

LinearTurboFold: Linear-time global prediction of conserved structures for RNA homologs with applications to SARS-CoV-2.Semantic proximity Read

Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanismsSemantic proximity Read