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Genome-wide association analysis of plasma lipidome identifies 495 genetic associations

2023-01-23

Abstract excerpt

Human plasma lipidome captures risk for cardio-metabolic diseases. To discover new lipid-associated variants and understand link between lipid species and cardiometabolic disorders, we performed univariate and multivariate genome-wide analyses of 179 lipid species in 7,174 Finnish individuals. We further fine-mapped the associated loci, prioritized genes, and examined their disease links in 377,277 FinnGen partici...

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Literature Corpus work: 6e74e862-1ad0-561c-ab09-0f0aa25f8268
DOI: 10.1101/2023.01.21.23284765

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