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Genetic architecture of human plasma lipidome and its link to cardiovascular disease

24 Sept 2019

Abstract excerpt

Abstract Understanding genetic architecture of plasma lipidome could provide better insights into lipid metabolism and its link to cardiovascular diseases (CVDs). Here, we perform genome-wide association analyses of 141 lipid species (n = 2,181 individuals), followed by phenome-wide scans with 25 CVD related phenotypes (n = 511,700 individuals). We identify 35 lipid-species-associated loci (P <5 ×10−8), 10 of...

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Share to Diabetes, Cardiovascular Risks, and Lipoproteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31551469
DOI: 10.1038/s41467-019-11954-8

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