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Article

Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study.

Journal of lipid research - 1 Apr 2020

Cadby Gemma, Melton Phillip E, McCarthy Nina S, Giles Corey, Mellett Natalie A, Huynh Kevin, Hung Joseph, Beilby John, Dubé Marie-Pierre, Watts Gerald F, Blangero John, Meikle Peter J, Moses Eric K

Abstract excerpt

CVD is the leading cause of death worldwide, and genetic investigations into the human lipidome may provide insight into CVD risk. The aim of this study was to estimate the heritability of circulating lipid species and their genetic correlation with CVD traits. Targeted lipidomic profiling was performed on 4,492 participants from the Busselton Family Heart Study to quantify the major fatty acids of 596 lipid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32060071
DOI: 10.1194/jlr.RA119000594
PMCID: PMC7112151

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