Article

Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4

2020-11-03

Abstract excerpt

Mechanisms by which non-coding genetic variation influences gene expression remain only partially understood but are considered to be major determinants of phenotypic diversity and disease risk. Here, we evaluated effects of >50 million SNPs and InDels provided by five inbred strains of mice on the responses of macrophages to interleukin 4 (IL-4), a cytokine that plays pleiotropic roles in immunity and tissue home...

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Literature Corpus work: 6e266808-d3e1-5168-b585-f930fbb84d86
DOI: 10.1101/2020.11.02.365742

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