Article

Epigenetic variation impacts ancestry-associated differences in the transcriptional response to influenza infection

2022-05-11

Abstract excerpt

<h4>Summary</h4> Humans display remarkable inter-individual variation in immune response when exposed to identical immune challenges. Yet, our understanding of the genetic and epigenetic factors contributing to such variation remains limited. Here we carried out in-depth genetic, epigenetic, and transcriptional profiling on primary macrophages derived from a panel of European and African-ancestry individuals befo...

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Literature Corpus work: 5f17805d-8183-5d0a-baf6-d4db7ac7f925
DOI: 10.1101/2022.05.10.491413

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