Article

<b>MARGE:</b> Mutation Analysis for Regulatory Genomic Elements

2018-02-21

Abstract excerpt

Cell-specific patterns of gene expression are determined by combinatorial actions of sequence-specific transcription factors at cis -regulatory elements. Studies indicate that relatively simple combinations of lineage-determining transcription factors (LDTFs) play dominant roles in the selection of enhancers that establish cell identities and functions. LDTFs require collaborative interactions with additional tra...

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Literature Corpus work: 7e58e370-a2d1-56b7-90c2-fe676e2cf7ac
DOI: 10.1101/268839

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