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Next-Generation Multiplexed Targeted Proteomics Quantifies Post-Translational Modifications, Compound-Protein Interactions, and Disease Biomarkers with High Throughput

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> The GoDig platform enables sensitive, multiplexed targeted pathway proteomics without manual scheduling or synthetic standards. Here we present GoDig 2.0, which increases sample multiplexing to 35-fold, improves time efficiency and reduces scan delays for higher success rates, and allows flexible spectral and elution library generation from different mass spectrometry data types. GoDig 2.0 measu...

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Literature Corpus work
6e051490-2c3f-5611-a644-c1ffa2e5a3a7
DOI
10.1101/2025.09.10.675380
Open publication

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Next-Generation Multiplexed Targeted Proteomics Quantifies Post-Translational Modifications, Compound-Protein Interactions, and Disease Biomarkers with High ThroughputDOI 10.1101/2025.09.10.675380
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