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Inserting Pre-Analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics With Sample Multiplexing

2024-02-08

Abstract excerpt

<h4>ABSTRACT</h4> GoDig, a recent platform for targeted pathway proteomics without the need for manual assay scheduling or synthetic standard peptides, is a relatively flexible and easy-to-use method that uses tandem mass tags (TMT) to increase sample throughput up to 18-fold relative to label-free targeted proteomics. Though the protein quantification success rate of GoDig is generally high, the peptide-level su...

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Identifiers and source

Literature Corpus work
8de725f7-855c-5135-bac2-b5608a44262f
DOI
10.1101/2024.02.08.579551
Open publication

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