Omic-Sig: Utilizing Omics Data to Explore and Visualize Kinase-Substrate Interactions

Abstract excerpt

Protein phosphorylation is one of the most prevalent post-translational modifications, resulting from the activity of protein kinases phosphorylating specific substrates. Multiple cellular processes are regulated via protein phosphorylation, with aberrant signaling driven by dysregulation of phosphorylation events and associating with disease progression (e.g., cancer). Mass spectrometry-based phosphoprotomics app...

Topics

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• Algorithms
• Bioinformatics and Genomic Networks
• Computational Biology
• Computational Drug Discovery Methods
• Microbial Natural Products and Biosynthesis
• Neoplasms
• Peptidase Inhibition and Analysis
• Ubiquitin and proteasome pathways

Identifiers and source

Literature Corpus work

5261c91d-59e6-5cc1-b72f-fc7824ce3dc9

DOI

10.1101/746123