Article
Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome.
Cell - 28 Jul 2016
Kusebauch Ulrike, Campbell David S, Deutsch Eric W, Chu Caroline S, Spicer Douglas A, Brusniak Mi-Youn, Slagel Joseph, Sun Zhi, Stevens Jeffrey, Grimes Barbara, Shteynberg David, Hoopmann Michael R, Blattmann Peter, Ratushny Alexander V, Rinner Oliver, Picotti Paola, Carapito Christine, Huang Chung-Ying, Kapousouz Meghan, Lam Henry, Tran Tommy, Demir Emek, Aitchison John D, Sander Chris, Hood Leroy, Aebersold Ruedi, Moritz Robert L
Abstract excerpt
The ability to reliably and reproducibly measure any protein of the human proteome in any tissue or cell type would be transformative for understanding systems-level properties as well as specific pathways in physiology and disease. Here, we describe the generation and verification of a compendium of highly specific assays that enable quantification of 99.7% of the 20,277 annotated human proteins by the widely...
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