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Spatial Multi-Omics Reveals Extracellular Matrix Remodeling and VSMC Phenotypic Switching in Moyamoya Disease

2026-04-30

Abstract excerpt

<h4>Background</h4> Moyamoya disease (MMD) is a progressive cerebrovascular disorder characterized by steno-occlusive lesions and intimal hyperplasia. Although vascular smooth muscle cell (VSMC) phenotypic switching is implicated in its pathogenesis, the precise spatial interplay between extracellular matrix (ECM) remodeling and local metabolic alterations within the distinct vascular microenvironments remains un...

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Literature Corpus work
6deb7498-3f35-53f3-bcf4-140a9c35a6a3
DOI
10.64898/2026.04.27.721225
Open publication

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Spatial Multi-Omics Reveals Extracellular Matrix Remodeling and VSMC Phenotypic Switching in Moyamoya DiseaseDOI 10.64898/2026.04.27.721225
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