Article

Single-Nucleus Atlas of Cell-Type Specific Genetic Regulation in the Human Brain

2024-12-11

Abstract excerpt

<title>Abstract</title> <p>Genetic risk variants for common diseases are predominantly located in non-coding regulatory regions and modulate gene expression. Although bulk tissue studies have elucidated shared mechanisms of regulatory and disease-associated genetics, the cellular specificity of these mechanisms remains largely unexplored. This study presents a comprehensive single-nucleus multi-ancestry atlas of...

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Literature Corpus work: 6dd5eb4f-dd28-5396-a56e-24bde028b8d0
DOI: 10.21203/rs.3.rs-5368620/v1

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