Article

Single-Nucleus Atlas of Cell-Type Specific Genetic Regulation in the Human Brain

2024-11-04

Abstract excerpt

Genetic risk variants for common diseases are predominantly located in non-coding regulatory regions and modulate gene expression. Although bulk tissue studies have elucidated shared mechanisms of regulatory and disease-associated genetics, the cellular specificity of these mechanisms remains largely unexplored. This study presents a comprehensive single-nucleus multi-ancestry atlas of genetic regulation of gene e...

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Literature Corpus work: bbac4759-398c-57f1-8cde-a6e63f9abc83
DOI: 10.1101/2024.11.02.24316590

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