Article

Single nucleus multi-omics links human cortical cell regulatory genome diversity to disease risk variants

2019-12-12

Abstract excerpt

<h4>ABSTRACT</h4> Single-cell technologies enable measure of unique cellular signatures, but are typically limited to a single modality. Computational approaches allow integration of diverse single-cell datasets, but their efficacy is difficult to validate in the absence of authentic multi-omic measurements. To comprehensively assess the molecular phenotypes of single cells in tissues, we devised single-nucleus m...

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Literature Corpus work: 51fff2cf-3415-55a2-988a-8b173f69aab7
DOI: 10.1101/2019.12.11.873398

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