Article

Single-cell genomics and regulatory networks for 388 human brains

2024-03-19

Abstract excerpt

Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet, little is understood about how genetic variants influence cell-level gene expression. Addressing this, we uniformly processed single-nuclei, multi-omics datasets into a resource comprising >2.8M nuclei from the prefrontal cortex across 388 individuals. For 28 cell types, we assessed population-level variation in expr...

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Literature Corpus work: 26d43190-a0ae-5637-a24b-e950ed7cddec
DOI: 10.1101/2024.03.18.585576

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