Article

Causal Mediation Analysis with Multiple Causally Ordered and Non-ordered Mediators based on Summarized Genetic Data

2021-01-08

Abstract excerpt

Causal mediation analysis aims to investigate the mechanism linking an exposure and an outcome. Dealing with the impact of unobserved confounders among the exposure, mediator and outcome has always been an issue of great concern. Moreover, when multiple mediators exist, this causal pathway intertwines with other causal pathways, making it more difficult to estimate of path-specific effects (PSEs). In this article,...

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Literature Corpus work: 6db5998c-83e7-5452-9b1a-b4fb1ab50f53
DOI: 10.1101/2021.01.07.21249415

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