Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mediation model with a categorical exposure and a censored mediator with application to a genetic study.

PloS one - 1 Jan 2021

Wang Jian, Ning Jing, Shete Sanjay

Abstract excerpt

Mediation analysis is a statistical method for evaluating the direct and indirect effects of an exposure on an outcome in the presence of a mediator. Mediation models have been widely used to determine direct and indirect contributions of genetic variants in clinical phenotypes. In genetic studies, the additive genetic model is the most commonly used model because it can detect effects from either recessive or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Computer Simulation
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Menopause

Share to Models, Genetic

Share to Models, Statistical

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 34637449
DOI: 10.1371/journal.pone.0257628
PMCID: PMC8509986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mediation model with a categorical exposure and a censored mediator with application to a genetic study.PMID 34637449Read ↗

Estimation of indirect effect when the mediator is a censored variable.Semantic proximity Read ↗

Multivariable Mendelian Randomization and Mediation.Semantic proximity Read ↗

A mediation analysis framework based on variance component to remove genetic confounding effect.Semantic proximity Read ↗

MELODY: Mediation Analysis in Logistic Regression for High-Dimensional Mediators and a Binary OutcomeSemantic proximity Read ↗

Mendelian randomisation for mediation analysis: current methods and challenges for implementation.Semantic proximity Read ↗

Penalized mediation models for multivariate data.Semantic proximity Read ↗

Causal Mediation Analysis with Multiple Causally Ordered and Non-ordered Mediators based on Summarized Genetic DataSemantic proximity Read ↗

Mediation analysis of multiple mediators with incomplete omics data.Semantic proximity Read ↗

DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysisSemantic proximity Read ↗

Efficient Estimation of Indirect Effects in Case-Control Studies Using a Unified Likelihood FrameworkSemantic proximity Read ↗

An approach to estimate bidirectional mediation effects with application to body mass index and fasting glucose.Semantic proximity Read ↗

A Bayesian model selection approach to mediation analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.