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Article

Multivariable Mendelian Randomization and Mediation.

Cold Spring Harbor perspectives in medicine - 1 Feb 2021

Sanderson Eleanor

Abstract excerpt

Mendelian randomization (MR) is the use of genetic variants associated with an exposure to estimate the causal effect of that exposure on an outcome. Mediation analysis is the method of decomposing the effects of an exposure on an outcome, which act directly, and those that act via mediating variables. These effects are decomposed through the use of multivariable analysis to estimate the causal effects between...

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Identifiers

PMID: 32341063
DOI: 10.1101/cshperspect.a038984
PMCID: PMC7849347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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